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2005 1
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Page 1
Osthole attenuated cytotoxicity induced by 6-OHDA in SH-SY5Y cells through inhibition of JAK/STAT and MAPK pathways.
Barangi S, Hosseinzadeh P, Karimi G, Tayarani Najaran Z, Mehri S. Barangi S, et al. Iran J Basic Med Sci. 2023;26(8):953-959. doi: 10.22038/IJBMS.2023.68292.14905. Iran J Basic Med Sci. 2023. PMID: 37427324 Free PMC article.
In this study, we explored how osthole protects human neuroblastoma SH-SY5Y cells from the cytotoxicity of 6-hydroxydopamine (6-OHDA). ...CONCLUSION: In summary, our data showed that osthole protects SH-SY5Y cells against 6-OHDA-induced cytotoxicity by inhibiting RO …
In this study, we explored how osthole protects human neuroblastoma SH-SY5Y cells from the cytotoxicity of 6-hydroxydopamine (6-OHDA) …
Novel Coumarin-Pyridine Hybrids as Potent Multi-Target Directed Ligands Aiming at Symptoms of Alzheimer's Disease.
Babaei E, Küçükkılınç TT, Jalili-Baleh L, Nadri H, Öz E, Forootanfar H, Hosseinzadeh E, Akbari T, Ardestani MS, Firoozpour L, Foroumadi A, Sharifzadeh M, Mirjalili BBF, Khoobi M. Babaei E, et al. Front Chem. 2022 Jun 30;10:895483. doi: 10.3389/fchem.2022.895483. eCollection 2022. Front Chem. 2022. PMID: 35844650 Free PMC article.
Compound 3f as the best AChE inhibitor (IC(50) = 2 nM) showed acceptable BuChE inhibition activity (IC(50) = 24 nM), 100 times more active than the standard drug. Compound 3f could also significantly protect PC12 and SH-SY5Y cells against H(2)O(2)-induced cell death and am …
Compound 3f as the best AChE inhibitor (IC(50) = 2 nM) showed acceptable BuChE inhibition activity (IC(50) = 24 nM), 100 times more active t …
Cedrol protects against chronic constriction injury-induced neuropathic pain through inhibiting oxidative stress and inflammation.
Sakhaee MH, Sayyadi SAH, Sakhaee N, Sadeghnia HR, Hosseinzadeh H, Nourbakhsh F, Forouzanfar F. Sakhaee MH, et al. Metab Brain Dis. 2020 Oct;35(7):1119-1126. doi: 10.1007/s11011-020-00581-8. Epub 2020 May 29. Metab Brain Dis. 2020. PMID: 32472224
The changes in the levels of biomarkers of oxidative stress including malondialdehyde (MDA) and total thiol (SH), as well as inflammatory mediators including Tumour Necrosis Factor alpha (TNF-alpha) and Interleukin 6 (IL-6) were estimated in the lumbar portion (L4-L6) of n …
The changes in the levels of biomarkers of oxidative stress including malondialdehyde (MDA) and total thiol (SH), as well as inflamma …
Preventive effects of crocin on neuronal damages induced by D-galactose through AGEs and oxidative stress in human neuroblastoma cells (SH-SY5Y).
Heidari S, Mehri S, Shariaty V, Hosseinzadeh H. Heidari S, et al. J Pharmacopuncture. 2018 Mar;21(1):18-25. doi: 10.3831/KPI.2018.21.003. Epub 2018 Mar 31. J Pharmacopuncture. 2018. PMID: 30151301 Free PMC article.
(saffron), against D-gal-induced cytotoxicity in human neuroblastoma SH-SY5Y cells. METHODS: Pretreated cells with crocin (25-500 muM, 24 h) were exposed to D-gal (25-400 mM, 48 h). ...Pretreatment of SHSY-5Y cells with crocin (500 muM) before adding D-gal significantly re …
(saffron), against D-gal-induced cytotoxicity in human neuroblastoma SH-SY5Y cells. METHODS: Pretreated cells with crocin (25-500 muM …
20 results